year
2023
keywords
NMR · MALDI-MS · cancer diagnostics · metabolomics · correlation spectroscopy
research
barman lab · jhu
projects / nmr & maldi-ms 2d correlation spectroscopy

NMR & MALDI-MS 2D Correlation Spectroscopy

statistical analysis of lipid–metabolite interactions in tumor models

Two-dimensional correlation analysis of NMR and MALDI mass spectrometry data to identify co-varying lipid and metabolite features in tumor cell models. Reveals spectral interactions that serve as candidate biomarkers for metabolic phenotyping in cancer diagnostics.

Contributions

  1. Developed cross-modal correlation framework pairing NMR chemical shift assignments with MALDI spatial features.
  2. Applied statistical filtering to isolate cancer-state-dependent spectral co-variance.
  3. Presented findings at JHU School of Medicine Radiology Research Day (Pre-Clinical Poster Award).